Hot Selling Pure Natural Posaconazole Powder
1-1000 Gram
$85.00
≥ 1001 Gram
$55.00
- Item No.PosaconazoleMOQ1 Gram
Choice
Quantity:
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
Hot Selling Pure Natural Posaconazole Powder
Production Name:Posaconazole CAS NO:171228-49-2 EINECS No.:N/A Molecular Formula:C37H42F2N8O4 MW:700.78 Category:API Appearance:White Powder Specification: 98% Test Method : HPLC
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Posaconazole is a triazole antifungal drug. It is used for the prophylaxis of invasive Aspergillus and Candida infections in patients who are at high risk of developing these infections due to being severely immunocompromised, such as HSCT recipients with GVHD or those with hematologic malignancies with prolonged neutropenia from chemotherapy. It is also used for the treatment of oropharyngeal candidiasis (OPC), including OPC refractory to itraconazole and/or fluconazole therapy. It is also used to treat invasive infections by Candida, Mucor, and Aspergillus species in severely immunocompromised patients.
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Posaconazole is a broadspectrum triazole active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14ademethylase enzyme (IC50s range from 7-200 nM), which results in a disruption the synthesis of ergosterol, a key sterol necessary for fungal cell membrane integrity and for the function of certain membranebound proteins.Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14alpha demethylase, a cytochrome P450-dependent enzyme. Posaconazole is a sterol C14a demethylase inhibitor with an IC50 of 0.25 nM. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters membrane permeability and eventually leads to fungal cell lysis. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14alpha demethylase. Posaconazole is the most advanced candidate for the treatment of Chagas disease. Posaconazole has entered in a phase II clinical trial in the treatment of mycoses.
Xi'an Macale Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
Macale's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. Macale Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
Macale's main products are plant extracts ,health products.
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
Q1:Are you a manufacturer or trading company?
A: We are a manufacturer, welcome to visit us.
Q2: What's your MOQ?
A:It depends on different products, we accept sample order or provide free samples for your
testing.
Q3: How to confirm the product quality before placing the order?
A:Sample could be provided, and we have inspection report issued by authoritative third-party
testing agency.
Q4:Can you send products to my country?
A: Sure, we can, we have rich shipping experience to the whole world.
Q5: How about delivery time/method?
A: We usually ship within 1-3 working days after your payment.
We can ship by door to door courier, by air, by sea, you could also use your own shipping
agent, if u have.
Q6. How to solve after-sale disputes?
A: We accept Changing or refunding service if any quality problem, u can pay via Alibaba to
protect your fund security.
Business Type | Trading Company | Country / Region | Shaanxi, China |
Main Products | API Raw Material,Vitamins,Cosmetics Raw,Plant extract,Antibiotics | Total Employees | 5 - 10 People |
Total Annual Revenue | Below US$1 Million | Year Established | 2019 |
Certifications | Product Certifications | ||
Patents | Trademarks | ||
Main Markets | Western Europe 25% North America 15% Eastern Europe 12% |
Xi'an Macale Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
Macale's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. Macale Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
Macale's main products are plant extracts ,health products,
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
Macale Corporation adheres to the corporate tenet of "scientific rigor, pioneering and innovative, sincere cooperation". "
Macale's corporate philosophy: "Integrity first, customer first. Sincere unity, open up the future."
With the improvement of people's quality of life in the new century, along with the vigorous development of the life and health industry, Macale Bio is facing greater opportunities and challenges. We are confident to provide more comprehensive and better scientific and technical services for scientific researchers. Macale will not humiliate its mission and create the future with you!
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