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High Quality Medicine grade Succimer dmsa dimercaptosuccinic acid
10-1009 Gram
$1.20
≥ 1010 Gram
$0.80
- Item No. dimercaptosuccinic acidMOQ 10 Gram
Choice
Quantity:
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If over 500pcs, mass production will start until pre-production sample has been approved.
Est. 7 days production
High Quality Medicine grade Succimer dmsa dimercaptosuccinic acid
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Dimercaptosuccinic Acid is the organosulfur compound with the formula HO2CCH(SH)CH(SH)CO2H. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour.
It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as achelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water soluble and non-toxic substance.
Dimercaptosuccinic Acid is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood–brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.
Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.
The relative activities of a series of novel monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) have been examined as agents for the mobilization of cadmium, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound DMSA.
Xi'an Macale Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
Macale's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. Macale Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
Macale's main products are plant extracts ,health products,
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
Q1:Are you a manufacturer or trading company?
A: We are a manufacturer, welcome to visit us.
Q2: What's your MOQ?
A:It depends on different products, we accept sample order or provide free samples for your
testing.
Q3: How to confirm the product quality before placing the order?
A:Sample could be provided, and we have inspection report issued by authoritative third-party
testing agency.
Q4:Can you send products to my country?
A: Sure, we can, we have rich shipping experience to the whole world.
Q5: How about delivery time/method?
A: We usually ship within 1-3 working days after your payment.
We can ship by door to door courier, by air, by sea, you could also use your own shipping
agent, if u have.
Q6. How to solve after-sale disputes?
A: We accept Changing or refunding service if any quality problem, u can pay via Alibaba to
protect your fund security.
| Business Type | Trading Company | Country / Region | Shaanxi, China |
| Main Products | API Raw Material,Vitamins,Cosmetics Raw,Plant extract,Antibiotics | Total Employees | 5 - 10 People |
| Total Annual Revenue | Below US$1 Million | Year Established | 2019 |
| Certifications | Product Certifications | ||
| Patents | Trademarks | ||
| Main Markets | Western Europe 25% North America 15% Eastern Europe 12% | ||
Xi'an Macale Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
Macale's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. Macale Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
Macale's main products are plant extracts ,health products,
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
Macale Corporation adheres to the corporate tenet of "scientific rigor, pioneering and innovative, sincere cooperation". "
Macale's corporate philosophy: "Integrity first, customer first. Sincere unity, open up the future."
With the improvement of people's quality of life in the new century, along with the vigorous development of the life and health industry, Macale Bio is facing greater opportunities and challenges. We are confident to provide more comprehensive and better scientific and technical services for scientific researchers. Macale will not humiliate its mission and create the future with you!
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